Mahmoud Kiaei, Ph.D. (Principal Investigator)
The goal of my laboratory is to develop animal models to study motor neuron disease and utilizes our extensive experience on pre-clinical studies for disease like ALS to unravel the mechanism of neurodegeneration. My lab uses these resources to develop drug discovery strategies in fulfilling the unmet need of patients.
Daniel Fil joined Dr. Kiaei’s lab in 2015. His research interests focus on neuroinflammation and neurodegeneration. In his current project he is involved in development of novel Profilin 1 (PFN1) ALS mouse model as well as investigating the mechanism by which mutated PFN1 leads to moto-neuron pathology and death.