I am pursuing my independent research project on proteasome mediated mitochondrial and renal damage. As a collaborator, I am helping Dr. MacMillan-Crow to study the molecular mechanisms that disrupt mitochondrial dynamics during renal cold storage and transplantation using our rat kidney transplant model. Our hypothesis is that increased mitochondrial fragmentation leads to renal damage during renal cold storage and transplantation. My specialized skill sets will be fundamental to this project of Dr. MacMillan-Crow. I will also help this project by training a new surgeon, who will be performing all rodent transplant surgeries. My enthusiasm as well as immense passion and creativity for this subject will certainly help us to investigate molecular mechanisms of kidney injury pre- and post-transplant.
Sorena Lo has worked in this lab since November 2016. Her responsibilities include performing quantitative and qualitative analyses for Sham and transplant samples, and maintaining and conducting cold storage treatment experiments to NRK cell.