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SPaT Annual Symposium

Systems Pharmacology and Toxicology (SPaT) Fourth Annual Symposium

May 9, 2017
9:00 a.m. – 3:00 p.m.
Walton Auditorium, Winthrop P. Rockefeller Cancer Institute

The Systems Pharmacology and Toxicology (SPaT) Annual Symposium (associated with the SPaT T32 training grant) held its fourth annual symposium featuring presentations by SPaT trainees and students from PCOL, INTX and IBS programs.   The keynote presentation was given by James H. Woods, PhD (University of Texas Health Science Center at San Antonio)

9:00-9:10 AM
Introductory Remarks
Philip R. Mayeux, Ph.D., Director, SPaT T32 Training Grant

9:10–9:35 AM
“Cardiovascular and locomotor effects of 3/4-methylenedioxypyrovalerone (MDPV)
in male and female Sprague-Dawley (SD) rats”
Samantha McClenahan, SPaT Trainee, Interdisciplinary Toxicology Graduate Program

9:35—10:00 AM
“Measuring barrier function in human esophageal mucosa”
Dolapo Adejumobi, SPaT Trainee, IBS Graduate Program

10:00 ‐10:25 AM
“Influence of KATP Channels on the Contractile Properties of Rat Mesenteric Lymph Vessels”
Brittney Garner, SPaT Trainee, Interdisciplinary Toxicology Graduate Program

10:25 ‐10:50 AM
“Use of the CRISPRi/dCas9::KRAB system to suppress gene expression”
Ryan MacLeod, COM/TRI Trainee, IBS Graduate Program

10:50-11:00 AM
Break/Poster Viewing

11:00 ‐11:25 AM
Novel interaction between a mitochondrial chaperone and protease during renal transplantation”
Julia Tobacyk, SPaT Trainee, Pharmacology Graduate Program

11:25 ‐11:50 AM
“The role of MitoBK channels in renal cold preservation”
Stephen Shrum, Former SPaT Trainee, IBS Graduate Program

11:50 ‐12:15 AM
“Training and development: Impulsive choice for milk reinforcement to predict drug abuse liability in rats”
Bill Hyatt, Former COM/TRI Trainee, IBS Graduate Program

12:15 – 12:45 PM
Luncheon

12:45 – 1:30 PM
Poster Viewing

1:30 – 2:30 PM
Keynote Presentation – James H. Woods, PhD
Research Professor, Department of Pharmacology
University of Texas Health Science Center at San Antonio
“Behavioral discoverie srelated to cholinergic pharmacology”

2:30 – 3:00 PM
Closing Remarks and Final Poster Viewing

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 Systems Pharmacology and Toxicology (SPaT) Third Annual Symposium

May 10, 2016
9:00 a.m. – 2:30 p.m.
Walton Auditorium, Winthrop P. Rockefeller Cancer Institute

The Systems Pharmacology and Toxicology (SPaT) Annual Symposium (associated with the SPaT T32 training grant) held its third annual symposium featuring presentations by the six 2015-2016 SPaT trainees, poster presentations by the three previous trainees and students from PCOL, INTX and IBS programs, as well as graduate students of SPaT Training Faculty.   The keynote presentation was given by Vishal Vaidya, PhD (Harvard Medical School)

DSC_1049

9:00-9:10 AM
Introductory Remarks
Philip R. Mayeux, Ph.D., Director, SPaT T32 Training Grant

9:10–9:35 AM
“Population variability in cisplatin-induced kidney injury outcomes are modeled using diversity outbred mice”
Julia Tobacyk, SPaT Trainee, Pharmacology Graduate Program

9:35—10:00 AM
“The role of mitoBK channels in renal cold preservation”
Stephen Shrum, SPaT Trainee, IBS Graduate Program

10:00 ‐10:25 AM
“The development of Anti-METH immunotherapies using adeno-associated viruses”
Chuck Hay, SPaT Trainee, Interdisciplinary Toxicology Graduate Program

10:25-10:40 AM
Break/Poster Viewing

10:40 ‐11:05 AM
“Effects of synthetic cathinones 3,4-methylenedioxypyrovalerone (MDPV) and
α-pyrrolidinovalerophenone (α-PVP) on impulsivity and vulnerability to psychostimulant abuse”
Bill Hyatt, COM/TRI Trainee, IBS Graduate Program

11:05 ‐11:30 AM
“Genetic background plays a role in risk of zileuton-induced liver injury in diversity outbred mice”
Lascelles Lyn-Cook Jr., SPaT Trainee, IBS Graduate Program

11:30 ‐11:55 AM
“Photoactivation of targeted “nanodrugs” for the eradication of Staphylococcus aureus biofilms”
Daniel Meeker, Former SPaT Trainee, IBS Graduate Program

12:00 – 1:30 PM
Luncheon/Poster Viewing

1:30 – 2:30 PM
Keynote Presentation – Vishal Vaidya, PhD
Associate Professor of Medicine & Environmental Health
Harvard Medical School, Harvard T.H. Chan School of Public Health, Brigham and Women’s Hospital
“Systems and Translational Approach to Understand Toxicology”

2:30 – 3:00 PM
Closing Remarks and Final Poster Viewing

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Systems Pharmacology and Toxicology (SPaT) Second Annual Symposium

May 7, 2015
10:00 a.m. – 2:30 p.m.
IDW Building, 2nd Floor

The Systems Pharmacology and Toxicology (SPaT) Annual Symposium (associated with the SPaT T32 training grant) held its second annual symposium featuring presentations by the four 2014-2015 SPaT trainees, plus two previous trainees, poster presentations by students from PCOL, INTX and IBS programs, as well as graduate students of SPaT Training Faculty, and a keynote presentation by Gary Petlz MD, PhD (Stanford University).

SPaT 2015

9:00—10:00AM
Registration and Poster Set Up

10:00—10:15AM
Introductory Remarks
Philip R. Mayeux, Ph.D., Director, SPaT T32 Trainin gGrant

10:15–10:35AM
“Design and Testing of Long Acting Viral Mediated Anti-METH Immunotherapies”
Chuck Hay, SPaT Trainee, Interdisciplinary Toxicology Graduate Program

10:35—10:55AM
Diversity Outbred Mice May Improve Preclinical Screening for Drug-Induced Liver Injury”
Lascelles Lyn-cook, SPaT Trainee, IBS Graduate Program

10:55 ‐11:15AM
“A Tiny Solution to a Huge Problem: Employing Antibiotic-Loaded Gold Nanocages to Kill Staphylococcus aureus”
Daniel Meeker, SPaT Trainee, IBS Graduate Program

11:15 ‐11:35AM
“ROS Signaling Differentially Regulates Bone Turnover in an Age-Specific Manner in Female Mice”
Alex Alund, SPaT Trainee, IBS Graduate Program

11:35 ‐11:55AM
“Targeting Oxidants in an Infant Model of Sepsis-Induced Cardiorenal Syndrome”
Clark Sims, Past SPaT Trainee, Pharmacology Graduate Program

11:55 ‐12:15AM
“Understanding the Role of Invasive Patterns and Stromal Response in the Development of Aggressive Vulvar Squamous Cell Carcinoma”
Emily Coffman Holthoff, Past SPaT Trainee,IBS Graduate Program

12:15 – 1:30 PM
Luncheon/Poster Viewing

1:30–2:30 PM
KeynotePresentation
Computational Genetics and Translational Discovery”
Gary Peltz, M.D., Ph.D., Professor of Anesthesiology
Perioperative and Pain Medicine, Stanford University

 2:00 – 2:30 PM
Closing Remarks and Final Poster Viewing

SPaT Program 2015 Keynote

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Systems Pharmacology and Toxicology (SPaT)  First Annual Symposium

May 12, 2014
10:00 a.m. – 2:30 p.m.
IDW Building, 2nd Floor

 The Systems Pharmacology and Toxicology (SPaT) Annual Symposium (associated with the SPaT T32 training grant) held its first annual symposium featuring presentations by the three 2013-2014 SPaT trainees, poster presentations by students from PCOL, INTX and IBS programs, as well as graduate students of SPaT Training Faculty, and a keynote presentation by Edward Sherwood MD, PhD (Vanderbilt University).

PharmToxic-symposium-SPAT

Program Agenda

9:00 – 10:00 AM
Registration and Poster Set Up

10:00 – 10:15 AM
Introductory Remarks
Philip R. Mayeux, Ph.D., Director, SPaT T32 Training Grant

10:15 – 10:45 AM
“Targeting Renal Perfusion and Mitochondrial Oxidants in a Model of Infant Sepsis”
Clark Sims, SPaT Trainee, Pharmacology Graduate Program

10:45 – 11:15 AM
“Protection Against Ethanol-Induced Osteopenia in Female Mice by Dietary Antioxidants’
Alex Alund, SPaT Trainee, IBS Graduate Program

11:15 – 11:45 AM
“Perineural Invasion as an Indicator of Clinical Outcome in Vulvar Carcinoma”
Emily Coffman Holthoff, SPaT Trainee, IBS Graduate Program

11:45 AM – 1:00 PM
Luncheon and Poster Viewing

1:00 – 2:00 PM
Keynote Presentation: Edward Sherwood, M.D., Ph.D.
Professor of Anesthesiology, Vice Chair for Research, Vanderbilt University
“Augmentation of antimicrobial immunity by TLR4 agonists”

2:00 – 2:30 PM
Closing Remarks and Final Poster Viewing

SPaT Sherwood