Spring 2021 Schedule
January 27 – Lance Benson
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19
Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Binder M, Loske J, Klasa C, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Völker MT, Müller SD, Liebert UG, Ishaque N, Kaderali L, Sander LE, Drosten C, Laudi S, Eils R, Conrad C, Landmesser U, Lehmann I.
February 3 – Francesca Lobianco
Renin-angiotensin system blockers, risk of SARS-CoV-2 infection and outcomes from CoViD-19: systemic review and meta-analysis
Lee MMY, Docherty KF, Sattar N, Mehta N, Kalra A, Nowacki AS, Solomon SD, Vaduganathan M, Petrie MC, Jhund PS, McMurray JJV
February 10 – Joel Vazquez
Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19
Hou T, Zeng W, Yang M, Chen W, Ren L, Ai J, Wu J, Liao Y, Gou X, Li Y, Wang X, Su H, Gu B, Wang J, Xu T.
February 17 – Postponed due to Inclement Weather
February 24 – Brian Parks
Alcohol increases exosome release from microglia to promote Complement C1q-induced cellular death of proopiomelanocortin neurons in the hypothalamus in a rat model of fetal alcohol spectrum disorders
Mukherjee S, Cabrera MA, Boyadjieva NI, Berger G, Rousseau B, Sarkar DK.
March 3 – Soumiya Pal
Mast cell-mediated antigen presentation regulates CD8+T cell effector functions
Stelekati, E, Bahri, R, D’Orlando, O, Orinska, Z, Mittrücker, HW, Langenhaun, R, Glatzel, M, Bollinger, A, Paus, R, Bulfone-Paus, S
Fall 2020 Schedule
September 2 – Lauren Russell
Dissertation Defense Practice
September 9 – Francesca Lobianco
COVID-19 vaccine development and a potential nanomaterial path forward.
Shin, M.D., Sourabh, S., Chung, Y.H., Beiss, V., Soo, K.C., Oscar, Ortega, O.A.O., Wirth, D.M. Chen, A., Sack, M., Pokorki, J.K., Steinmetz, N.F.
September 16 – Amal Shoeib
Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver.
Habib, A., Chokr, D., Wan, J., Hedge, P., Mabire, M., Seibert, M., Ribeiro, M.P., Le Gall, M., Letteron, P., Pilard, N., Mansouri, A., Brouillet, A., Tardelli, M., Weiss, E., Le Faouder, P., Guillou, H., Cravatt, B.F., Moreau, R., Trauner, M., Lotersztajn, S.
September 23 – Cathryn Wilson
Cannabidiol improves survival and behaviroural co-morbidities of Dravet syndrom in mice .
Patra, H., P., Serafeimidou, P., E., Bazelot, M., Walley, B., J., Williams, C., M., McNeish, A., J.
October 7 – Lance Benson and Soumiya Pal
L-type Ca 2+channel blockers promote vascular remodeling through activation of STIM proteins.
Johnson, M.T., Gudlur, A., Zhang, X., Xin, P., Emrich, S. M., Yoast, R.E., Courjaret, R., Nwokonko, R.M., Li, W., Hempel, N., Machaca, K., Gill, D.L., Hogan, P., G., Trebak, M.
October 14 – Christian Cabanlong
The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis.
Silva, J.P., Carmo, H., Carvalho, F.
October 21 – Brian Parks and Lance Benson
Opioid presynaptic disinhibiton of the midbrian periaqueductal grey descending analgesic pathway.
Lau, B.K., Winters, B.L., Vaughn, C.W.
October 28 – Amal Shoeib and Joel Vazquez
Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury
Cho, T., Wang, X., Uetrecht, J.
November 4 – Soumiya Pal and Brian Parks
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hyperetensive Rats.
Mukohda, M., Mizuno, R., Ozark, H.
November 18 – Francesca LoBianco
Efficacy and Safety of Transarterial Chemoembolization Plus External Beam Radiotherapy vs Sorafenib in Hepatocellular Carcinoma With Macroscopic Vascular Invasion.
Yoon, S.M., Ryoo, B.Y., Lee, S.J., Kim, J.H., Shin, J.H., An, J.H., Lee, H.C., Lim, Y.K.
December 2 – Lance Benson and Brian Parks
The Purinergic Receptor P2RX7 directs Metabolic Fitness of Long-Lived Memory CD8+ T Cells
da Silva, H.B., Beura, L.K., Wang, H., Hanse, E.A., Gore, R., Scott, M.C., Walsh, D.A., Block, K.E., Fonesca, R., Yan, Y., Hippen, K.L., Blazar, B.R., Masopust, D., Kelekar, A., Vulchanova, L., Hogquist, K.A., Jameson, S.C.
December 9 – Joel Vazquez and Soumiya Pal
Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lympathic System
Burchill, M.A., Finlon, J.M., Goldberg, A.R., Gillen, A.E., Dahms, P.A., McMahan, R.H., Tye, A., Winter, A.B., Reisz, J.A., Bohrnsen, E., Schafer, J.B., D’Alessandro, A., Orlicky, D.J., Kriss, M.S., Rosen, H.R., McCullough, R.L., Tamburini, B.A.J.
Spring 2020 Schedule
January 26 – Joel Vazquez and Melissa Clemens will present:
Hepatocyte Deletion of Triglyceride-Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice.
Gluchowski, N.L., Gabriel, K.R., Chitraju, C., Bronson, R.T., Mejhert, N., Boland, S., Wang, K., Lai, Z.W., Farese, R.V., Jr., Walther, T.C.,
Hepatology. 2019 Dec;70(6):1972-1985. doi: 10.1002/hep.30765. Epub 2019 Jun 26. PMID 31081165, PMCID: PMC6893913
February 5 – David Henry and Francesca Lobianco will present:
Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis.
Suchard, M.A., Schuemie, M.J., Krumholz, H.M., You, S.C., Chen, R., Pratt, N., Reich, C.G., Duke, J., Madigan, D., Hripcsak, G., Ryan, P.B.,
Lancet. 2019 Nov 16;394(10211):1816-1826. doi: 10.1016/S0140-6736(19)32317-7. Epub 2019 Oct 24.
PMID: 31668726, PMCID: PMC6924620
February 12 – Amal Shoeib and Christian Cabanalong will present
Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse.
Ruehle, S., Wager-Miller, J., Straiker, A., Farnsworth, J. Murphy, M.N., Loch, S., Monory, K., Mackie, K., Lutz B.,
J Neurochem. 2017 Aug;142(4):521-533. doi: 10.1111/jnc.14099. Epub 2017 Jul 18. PMID: 28608535, PMCID: PMC5554085
February 19 – Melissa Clemens and David Henry
Cerebral collateral therapeutics in acute ischemic stroke: A randomized preclinical trial of four modulation strategies.
Beretta, S., Versace, A., Carone, D., Riva, M., Dell’Era, V., Cuccione, E., Cai, R., Monza, L., Pirovano, S., Padovano, G., Stiro, F., Presotto, L., Paternò, G., Rossi, E., Giussani, C., Sganzerla, E.P., Ferrarese, C.,
Feb. 26 – Christian Cabanlong and Joel Vazquez will present:
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.
Cai, B., Dongiovanni, P., Corey, K.E, Wang, X., Shmarakov, I.O., Zheng, Z., Kasikara, C., Davra, V., Meroni, M., Chung, R.T., Rothlin, C.V, Schwabe, R.F., Blaner, W.S., Birge, R.B., Valenti, L., Tabas, I. PMID: 31839486, PMCID: PMC7004886
March 4 – Soumiya Pal and Lance Benson will present
Sympathetic enhancement of memory T cell homing and hypertension sensitization.
Xiao, L., Do, Carmo, L., Foss, J.D., Chen, W., Harrison, D.G., PMID: 31928179
April 1 – Brian Parks and Saki Fukuda to jointly present
In vivo brain GPCR signaling elucidated by phosphoproteomics.
Liu, J.J., Sharma, K., Zangrandi, L., Chen, C., Humphrey, S.J., Chiu, Y.T., Spetea, M.,, Liu-Chen, L.Y., Schwarzer, C., Mann, M.,PMID: 29930108,
PMCID: PMC6527112
April 15 – Lance Benson and Soumiya Pal will present
Epsin deficiency promotes lymphangiogenesis through regulation of VEGF3 degradation in diabetes.
Wu, H., Rahman, H,N,A, Dong,Y., Liu, X., Lee, Y., Wen, A., To,H.T., Xiao,L., Birsner, A.E., Bazinet, L., Wong,S., Song, K., Brophy, M.L., Mahamud, M.R., Baojun,C., Cai, X., Pasula, S., Kwak, S., Yang, W., Bischoff, J., Xu, J., Bielenberg, D.R., Dixon, J.B., J.D., Robert, Srinivasan, S.R., and C, Hong, PMID: 30102256, PMCID: PMC6118634,
Fall 2019 Schedule
September 4, 2019 – Melissa Clemens will present:
Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C-C Motif) Receptor 2-Positive Macrophages and Lipolysis.
Kim SJ, Feng D, Guillot A, Dai S, Liu F, Hwang S, Parker R, Seo W, He Y, Godlewski G, Jeong WI, Lin Y, Qin X, Kunos G, Gao B.
Hepatology. 2019 May;69(5):1965-1982. doi: 10.1002/hep.30525. Epub 2019 Mar 18. PMID: 30681731
September 11, 2019 – David Henry will present:
Cerebral collateral flow defines topography and evolution of molecular penumbra in experimental ischemic stroke.
Beretta S, Cuccione E, Versace A, Carone D, Riva M, Padovano G, Dell’Era V, Cai R, Monza L, Presotto L, Rousseau D, Chauveau F, Paternò G, Pappadà GB, Giussani C, Sganzerla EP, Ferrarese C.
Neurobiol Dis. 2015 Feb;74:305-13. doi: 10.1016/j.nbd.2014.11.019. Epub 2014 Dec 5. PMID: 25484287
September 18, 2019 – Joel Vazquez will present:
Arsenic May Act as a Pro-Metastatic Carcinogen Through Promoting Tumor Cell-Induced Platelet Aggregation.
Kim K, Heo YK, Chun S, Kim CH, Bian Y, Bae ON, Lee MY, Lim KM, Chung JH.
Toxicol Sci. 2019 Mar 1;168(1):18-27. doi: 10.1093/toxsci/kfy247. PMID: 30428081
September 25, 2019 – Amal Shoeib will present:
Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.
Maor Y, Yu J, Kuzontkoski PM, Dezube BJ, Zhang X, Groopman JE.
Genes Cancer. 2012 Jul;3(7-8):512-20. doi: 10.1177/1947601912466556. PMID: 23264851
October 2, 2019 – Christian Cabanalong will present:
Thermolytic Degradation of Synthetic Cannabinoids: Chemical Exposures and Pharmacological Consequences.
Thomas BF, Lefever TW, Cortes RA, Grabenauer M, Kovach AL, Cox AO, Patel PR, Pollard GT, Marusich JA, Kevin RC, Gamage TF, Wiley JL.
J Pharmacol Exp Ther. 2017 Apr;361(1):162-171. doi: 10.1124/jpet.116.238717. Epub 2017 Jan 13. Erratum in: J Pharmacol Exp Ther. 2017 May;361(2):245. PMID: 28087785
October 16, 2019 – Francesca Lobianco will present:
DMAPT is an Effective Radioprotector from Long-Term Radiation-Induced Damage to Normal Mouse Tissues In Vivo.
Morel KL, Ormsby RJ, Klebe S, Sweeney CJ, Sykes PJ.
Radiat Res. 2019 Aug;192(2):231-239. doi: 10.1667/RR15404.1. Epub 2019 May 16. PMID: 31095445
October 23, 2019 – David Henry & Laura Ewing will present:
Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration.
Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, Zhang L, Liu Q, Li Y, Li Y, Zhao H, Liu K, Lu J, Zhou Y, Huang P, Nie Y, Yan Y, Hui L, Lui KO, Zhou B.
Nat Commun. 2016 Nov 18;7:13369. doi: 10.1038/ncomms13369. PMID: 27857132
October 30, 2019 – Laura Ewing & Francesca Lobianco will present:
Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice.
Zhu F, Guo R, Wang W, Ju Y, Wang Q, Ma Q, Sun Q, Fan Y, Xie Y, Yang Z, Jie Z, Zhao B, Xiao L, Yang L, Zhang T, Liu B, Guo L, He X, Chen Y, Chen C, Gao C, Xu X, Yang H, Wang J, Dang Y, Madsen L, Brix S, Kristiansen K, Jia H, Ma X.
Mol Psychiatry. 2019 Aug 7. doi: 10.1038/s41380-019-0475-4. [Epub ahead of print] PMID: 31391545
November 6, 2019 – Amal Shoeib & Christian Cabanalong will present:
Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction.
Gao F, Kataoka M, Liu N, Liang T, Huang ZP, Gu F, Ding J, Liu J, Zhang F, Ma Q, Wang Y, Zhang M, Hu X, Kyselovic J, Hu X, Pu WT, Wang J, Chen J, Wang DZ.
Nat Commun. 2019 Apr 17;10(1):1802. doi: 10.1038/s41467-019-09530-1. PMID: 30996254
November 13, 2019 – Francesca Lobianco & Melissa Clemens will present:
Cardiac macrophages promote diastolic dysfunction.
Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.
J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16. PMID: 29339450
November 20, 2019 – Melissa Clemens & Joel Vazquez will present:
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.
Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD, Patapoutian A.
Science. 2018 Oct 26;362(6413):464-467. doi: 10.1126/science.aau6324. PMID: 30361375
December 4, 2019 – Christian Cabanalong & Amal Shoeib will present:
Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects.
Han Y, Sun CY, Meng SQ, Tabarak S, Yuan K, Cao L, Yan W, Xu LZ, Deng JH, Zhu WL, Li JL, Lu L, Xue YX, Shi J.
Mol Psychiatry. 2019 Aug 2. doi: 10.1038/s41380-019-0470-9. [Epub ahead of print] PMID: 31375779
December 11, 2019 – Joel Vazquez & David Henry will present:
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension.
Faraco G, Sugiyama Y, Lane D, Garcia-Bonilla L, Chang H, Santisteban MM, Racchumi G, Murphy M, Van Rooijen N, Anrather J, Iadecola C.
J Clin Invest. 2016 Dec 1;126(12):4674-4689. doi: 10.1172/JCI86950. Epub 2016 Nov 14. PMID: 27841763
December 18, 2019 – Laura Ewing will present:
Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity.
Groselj B, Ruan JL, Scott H, Gorrill J, Nicholson J, Kelly J, Anbalagan S, Thompson J, Stratford MRL, Jevons SJ, Hammond EM, Scudamore CL, Kerr M, Kiltie AE.
Mol Cancer Ther. 2018 Feb;17(2):381-392. doi: 10.1158/1535-7163.MCT-17-0011. Epub 2017 Aug 24. PMID: 28839000
Spring 2019 Schedule
January 9, 2019 – Samantha McClenahan & Laura Ewing
https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13030
Bosnano JS, Banks ML, Kolanos R, Sakloth F, Barnier ML, Glennon RA, Cozzi NV, Partilla JS, Baumann MH, Negus SS. Quantitative structure-activity relationship analysis of the pharmacology of para-substituted methcathinone analogues. British Journal of Pharmacology. 2015, May; 172(10):2433-2444. PMID: 25438806.
January 16, 2019 – David Henry & Lauren Russell
http://stm.sciencemag.org/content/10/426/eaan4488.short
Sagiv-Barfi I, Czerwinkski DK, Levy S, Alam IS, Mayer AT, Gambhir SS, Levy R. Eradication of spontaneous malignancy by local immunotherapy. Science Translational Medicine. 2018, Jan 31; 10(426): eaan4488. PMID: 29386357
January 23, 2019 – Cancelled
January 30, 2019 – Julia Tobacyk & Amal Shoeib
https://www.nature.com/articles/s41598-017-13282-7
Carhart-Harris RL, Roseman L, Bolstridge M, Demetriou L, Pannekoek JN, Wall MB, Tanner M, Kaelen M, McGonigle J, Murphy K, Leech R, Curran HV, Nutt DJ. Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Sci Rep. 2017, Oct 13; 7(1): 13187. PMID: 29030624
February 6, 2019 – Cancelled
February 13, 2019 – Kyle Urquhart & Julia Tobacyk
http://molpharm.aspetjournals.org/content/88/2/335.long
Thompson GL, Lane JR, Coudrat T, Sexton PM, Christopoulos A, Canals M. Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid Receptor. Mol Pharmacol. 2015 Aug; 88(2): 335-46. PMID: 2601354
February 20, 2019 – Brittney Garner & David Henry
https://www.sciencedirect.com/science/article/pii/S2211124718315031?via%3Dihub
Chakraborty S, Galla S, Cheng X, Yeo J-Y, Mell B, Singh V, Yeoh B, Saha P, Mathew AV, Vijay-Kumar M, Joe B. Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension. Cell Rep. 2018 Oct 16;25(3):677-689.e4. PMID: 30332647
February 27, 2019 – Christian Cabanlong & Brittney Garner
http://molpharm.aspetjournals.org/content/88/2/368.long
Khajehali E, Malone DT, Glass M, Sexton PM, Christopoulos A, Leach K. Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor. Mol Pharmacol. 2015 Aug; 88(2): 368-379. PMID: 26044547
March 6, 2019 – Stephen Shrum & Kyle Urquhart
https://onlinelibrary.wiley.com/doi/full/10.1111/adb.12639
Hemby SE, McIntosh S, Leon F, Cutler SJ, McCurdy CR. Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine. Addict Biol. 2018 Jun 27. doi: 10.1111/adb.12639. PMID: 29949228
March 13, 2019 – Cancelled
March 20, 2019 – Spring Break
March 27, 2019 – Allie Davis & Stephen Shrum
https://www.nature.com/articles/nature18928
Hayakawa K, Esposito E, Wang X, Terasaki Y, Liu Y, Changhong X, Ji X, Lo EH. Transfer of mitochondria from astrocytes to neurons after stroke. Nature. 2016 Jul 28; 535(7613):551-555. PMID: 27466127
April 3, 2019 – Laura Ewing & Allie Davis
https://www.pnas.org/content/112/51/E7138.long
Wheeler DS, Underhill SM, Stolz DB, Murdoch GH, Thiels E, Romero G, Amara SG. Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51): E7138-47. PMID: 26553986
April 17, 2019 – Melissa Clemens & Christian Cabanlong
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191299
Barry RL, Byun NE, Williams JM, Siuta MA, Tantawy MN, Speed NK, Saunders C, Galli A, Niswender KD, Avison MJ. Brief exposure to obesogenic diet disrupts brain dopamine networks. PLoS One. 2018 Apr 26;13(4):e0191299. PMID: 29698491
April 24, 2019 – Amal Shoeib & Melissa Clemens
https://www.pnas.org/content/115/50/12616.long
Milojevic S, Radicchi F, Walsh JP. Changing demographics of scientific careers: the rise of the temporary workforce. PNAS. 2018, Dec 11; 115(50): 12616-12623. PMID: 3053069
Fall 2018 Schedule
September 5, 2018 – Julia Tobacyk & Samantha McClenahan
Bogenschutz MP, Forcehimes AA, Pommy JA, Wilcox CE, Barbosa PC, Strassman RJ. Psilocybin-assisted treatment for alcohol dependence: a proof-of-concept study. J Psychopharmacol. 2015 Mar;29(3):289-99. doi: 10.1177/0269881114565144. Epub 2015 Jan 13. PMID: 25586396
September 12, 2018 – Chris Bolden & Lauren Russell
http://jpet.aspetjournals.org/content/344/3/708.long
DeWire SM, Yamashita DS, Rominger DH, Liu G, Cowan CL, Graczyk TM, Chen XT, Pitis PM, Gotchev D, Yuan C, Koblish M, Lark MW, Violin JD. A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine. J Pharmacol Exp Ther. 2013 Mar;344(3):708-17. doi: 10.1124/jpet.112.201616. Epub 2013 Jan 8. PMID: 23300227
September 19, 2018 – Christian Cabanlong & David Henry
https://www.sciencedirect.com/science/article/pii/S0140673612620893?via%3Dihub
Moodie R, Stuckler D, Monteiro C, Sheron N, Neal B, Thamarangsi T, Lincoln P, Casswell S; Lancet NCD Action Group. Profits and pandemics: prevention of harmful effects of tobacco, alcohol, and ultra-processed food and drink industries. Lancet. 2013 Feb 23;381(9867):670-9. doi: 10.1016/S0140-6736(12)62089-3. Epub 2013 Feb 12. PMID: 23410611
September 26, 2018 – Melissa Clemens & Samantha McClenahan
Simmler LD, Buser TA, Donzelli M, Schramm Y, Dieu LH, Huwyler J, Chaboz S, Hoener MC, Liechti ME. Pharmacological characterization of designer cathinones in vitro. Br J Pharmacol. 2013 Jan;168(2):458-70. doi: 10.1111/j.1476-5381.2012.02145.x. PMID: 22897747
October 3, 2018 – Lauren Russell & Julia Tobacyk
Jiang M, Wei Q, Dong G, Komatsu M, Su Y, Dong Z. Autophagy in proximal tubules protects against acute kidney injury. Kidney Int. 2012 Dec;82(12):1271-83. doi: 10.1038/ki.2012.261. Epub 2012 Aug 1. PMID: 22854643
October 10, 2018 – Stephen Shrum & Kyle Urquhart
Ishihara M, Urushido M, Hamada K, Matsumoto T, Shimamura Y, Ogata K, Inoue K, Taniguchi Y, Horino T, Fujieda M, Fujimoto S, Terada Y. Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury. Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F495-509. doi: 10.1152/ajprenal.00642.2012. Epub 2013 May 22. PMID: 2368117
October 18, 2018 – Kyle Urquhart & Chris Bolden
Morales AI, Detaille D, Prieto M, Puente A, Briones E, Arévalo M, Leverve X, López-Novoa JM, El-Mir MY. Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway. Kidney Int. 2010 May;77(10):861-9. doi: 10.1038/ki.2010.11. Epub 2010 Feb 17. PMID: 20164825
October 24, 2018 – Brittney Garner & Catheryn Wilson
https://www.sciencedirect.com/science/article/pii/S0085253815558353?via%3Dihub
Sorensen MV, Grossmann S, Roesinger M, Gresko N, Todkar AP, Barmettler G, Ziegler U, Odermatt A, Loffing-Cueni D, Loffing J. Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice. Kidney Int. 2013 May;83(5):811-24. doi: 10.1038/ki.2013.14. Epub 2013 Feb 27. PMID: 23447069
October 31, 2018 – Melissa Clemens & Laura Ewing
De Miguel C, Guo C, Lund H, Feng D, Mattson DL. Infiltrating T lymphocytes in the kidney increase oxidative stress and participate in the development of hypertension and renal disease. Am J Physiol Renal Physiol. 2011 Mar;300(3):F734-42. doi: 10.1152/ajprenal.00454.2010. Epub 2010 Dec 15. PMID: 21159736
November 7, 2018 – Catheryn Wilson & Stephen Shrum
Nikolaev VO1, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science. 2010 Mar 26;327(5973):1653-7. doi: 10.1126/science.1185988. Epub 2010 Feb 25. PMID: 20185685
November 14, 2018 – David Henry & Brittney Garner
Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ. Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway. J Pharmacol Exp Ther. 2012 Apr;341(1):274-84. doi: 10.1124/jpet.111.190132. Epub 2012 Jan 20. PMID: 22267202
November 28, 2018 – Laura Ewing & Christian Cabanlong
McNeil BD, Pundir P, Meeker S, Han L, Undem BJ, Kulka M, Dong X. Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature. 2015 Mar 12;519(7542):237-41. doi: 10.1038/nature14022. Epub 2014 Dec 17. PMID: 25517090